320369-81-1
Chemical Structure
Laccaridione B
- CAS No.: 320369-81-1
- Formula:C23H26O6
- Molecular Weight:398.45
InChIKey: UMMLLCGZZRNVRG-MDWZMJQESA-N
SMILES: CCOC1C2=C(C=C(O1)/C(C)=C/C(C)CC)C=C3C(C(C(C(OC)=C3)=O)=O)=C2O
Biological Activity: Laccaridione B can inhibit the activity of antiserine protease. Laccaridione B inhibits trypsin, papain, thermophilic protease, collagenase and zinc protease with IC50s of 10.9 μg/mL, 5.1 μg/mL, 8.4 μg/mL, 5.7 μg/mL and 3.0 μg/mL, respectively. Laccaridione B also has a strong anti-proliferative activity against L-929, K-562 and HeLa cells with IC50s of 2.4 μg/mL, 1.8 μg/mL and 13.9 μg/mL, respectively[1].
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Laccaridione B | Laccaridione B can inhibit the activity of antiserine protease. Laccaridione B inhibits trypsin, papain, thermophilic protease, collagenase and zinc protease with IC50s of 10.9 μg/mL, 5.1 μg/mL, 8.4 μg/mL, 5.7 μg/mL and 3.0 μg/mL, respectively. Laccaridione B also has a strong anti-proliferative activity against L-929, K-562 and HeLa cells with IC50s of 2.4 μg/mL, 1.8 μg/mL and 13.9 μg/mL, respectively. | |||||||||||||||||||||
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Keywords
