325466-03-3
Chemical Structure
(S,R)-Bis(monomyristoylglycero)phosphate ammonium
- CAS No.: 325466-03-3
- Formula:C34H70NO10P
- Molecular Weight:683.89
IUPAC Name: (2S)-2-hydroxy-3-((hydroxy((R)-2-hydroxy-3-(tetradecanoyloxy)propoxy)phosphoryl)oxy)propyl tetradecanoate, ammonia salt
InChIKey: NNTPILCZAQYMLP-CWZMXPKOSA-N
SMILES: CCCCCCCCCCCCCC(OC[C@@H](O)COP(OC[C@@H](O)COC(CCCCCCCCCCCCC)=O)(O)=O)=O.N
Biological Activity: (S,R)-Bis(monomyristoylglycero)phosphate ammonium actively contributes to cargo sorting by promoting the degradation and sorting of lipids, and it plays a critical role in the sorting of polyunsaturated fatty acids (PUFAs) within acidic organelles. This phospholipid features two phosphate-linked glycerol molecules arranged in a unique sn-1 glycerophospho-sn-1′ glycerol stereoconformation, with each glycerol molecule esterified to a myristic acid. Typically, it is found in the intraluminal vesicles (ILVs) of late endosomes and lysosomes.
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(S,R)-Bis(monomyristoylglycero)phosphate ammonium | (S,R)-Bis(monomyristoylglycero)phosphate ammonium actively contributes to cargo sorting by promoting the degradation and sorting of lipids, and it plays a critical role in the sorting of polyunsaturated fatty acids (PUFAs) within acidic organelles. This phospholipid features two phosphate-linked glycerol molecules arranged in a unique sn-1 glycerophospho-sn-1′ glycerol stereoconformation, with each glycerol molecule esterified to a myristic acid. Typically, it is found in the intraluminal vesicles (ILVs) of late endosomes and lysosomes. | |||||||||||||||||||||
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