332376-42-8
Chemical Structure
Antitrypanosomal agent 8
- CAS No.: 332376-42-8
- Formula:C23H19N5O2S
- Molecular Weight:429.49
IUPAC Name: N-(4-acetylphenyl)-2-((4-phenyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide
InChIKey: HZXNKHNEYNDVHW-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(C(C)=O)C=C1)CSC2=NN=C(C3=CC=NC=C3)N2C4=CC=CC=C4
Biological Activity: Antitrypanosomal agent 8 (compound 3b) has potent antitrypanosomal activity against Trypanosoma brucei with an IC50 value of 0.79 μM and exhibits certain cytotoxicity in L6 cells (IC50=80.95 μM)[1].
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Antitrypanosomal agent 8 | Antitrypanosomal agent 8 (compound 3b) has potent antitrypanosomal activity against Trypanosoma brucei with an IC50 value of 0.79 μM and exhibits certain cytotoxicity in L6 cells (IC50=80.95 μM). | |||||||||||||||||||||
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Keywords