3411-37-8
3411-37-8
Chemical Structure
Sophoranol
- CAS No.: 3411-37-8
- Formula:C15H24N2O2
- Molecular Weight:264.36
IUPAC Name: (41R,7aR,13aR,13bR)-7a-hydroxydodecahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one
InChIKey: VQYBAEAOOJBSTR-QHSBEEBCSA-N
SMILES: O=C1CCC[C@]2([H])[C@@]3([H])CCCN4[C@@]3([H])[C@](CCC4)(O)CN21
Biological Activity: Sophoranol is an alkaloid that can be isolated from S. flavescens, with antiviral activity. Sophoranol has anti-HBV (hepatitis B virus) activity. Sophoranol shows potent antiviral activities against respiratory syncytial virus (RSV) with an IC50 of 10.4 μg/mL[1][2].
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Sophoranol | Sophoranol is an alkaloid that can be isolated from S. flavescens, with antiviral activity. Sophoranol has anti-HBV (hepatitis B virus) activity. Sophoranol shows potent antiviral activities against respiratory syncytial virus (RSV) with an IC50 of 10.4 μg/mL. | |||||||||||||||||||||
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References
- [1]. Guan Ye, et al. LC-MS characterization of efficacy substances in serum of experimental animals treated with Sophora flavescens extracts. Biomed Chromatogr. 2007 Jun;21(6):655-60. [Content Brief]
- [2]. Shuang-Cheng Ma, et al. Antiviral Chinese medicinal herbs against respiratory syncytial virus. J Ethnopharmacol. 2002 Feb;79(2):205-11. [Content Brief]
Keywords
