349573-58-6
349573-58-6
Chemical Structure
AR antagonist 3
- CAS No.: 349573-58-6
- Formula:C15H18N2O3S
- Molecular Weight:306.38
InChIKey: VOOWYFBNDLFQKS-UHFFFAOYSA-N
SMILES: CN(S(=O)(NC1=CC=C(C=C1)OCC2=CC=CC=C2)=O)C
Biological Activity: AR antagonist 3 is a potent and selective androgen receptor (AR) antagonist with an IC50 of 0.47 µM. AR antagonist 3 exhibits a dose-dependent decrease of the FRET signal (IC50= 18.05 μM). AR antagonist 3 shows effective inhibition on tumor growth when administered intratumorally[1].
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AR antagonist 3 | 99.96% | AR antagonist 3 is a potent and selective androgen receptor (AR) antagonist with an IC50 of 0.47 µM. AR antagonist 3 exhibits a dose-dependent decrease of the FRET signal (IC50= 18.05 μM). AR antagonist 3 shows effective inhibition on tumor growth when administered intratumorally. | ||||||||||||||||||||
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References
Keywords
