3637-11-4
3637-11-4
Chemical Structure
Tempone-H
- CAS No.: 3637-11-4
- Formula:C9H17NO2
- Molecular Weight:171.24
IUPAC Name: 1-hydroxy-2,2,6,6-tetramethylpiperidin-4-one
InChIKey: KMEUSKGEUADGET-UHFFFAOYSA-N
SMILES: O=C1CC(C)(C)N(O)C(C)(C)C1
Biological Activity: Tempone-H may be used as a spin trap in chemical and biological systems to quantify peroxynitrite and superoxide radical formation. Ferric and cupric ions are effective oxidants of Tempone-H[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Tempone-H | 98.0% | Tempone-H may be used as a spin trap in chemical and biological systems to quantify peroxynitrite and superoxide radical formation. Ferric and cupric ions are effective oxidants of Tempone-H. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.90
HY-129242Tempone -
Similarity Score 0.83
HY-N1131ATriacetonamine hydrochloride -
Similarity Score 0.83
HY-N1131BTriacetonamine monohydrate -
Similarity Score 0.82
HY-N1131Triacetonamine -
Similarity Score 0.79
HY-100561Tempol -
Similarity Score 0.78
HY-W001187RTempo (Standard) -
Similarity Score 0.78
HY-N16482,2,5,5-Tetramethylcyclohexane-1,4-dione -
Similarity Score 0.78
HY-W0020044-Amino-TEMPO -
Similarity Score 0.77
HY-N17282-Ethyl-2,6,6-trimethylpiperidin-4-one -
Explore the MedChemAI to find more analogs
References
- [1]. Dikalov S, et al. Quantification of peroxynitrite, superoxide, and peroxyl radicals by a new spin trap hydroxylamine 1-hydroxy-2,2,6,6-tetramethyl-4-oxo-piperidine. Biochem Biophys Res Commun. 1997 Jan 3;230(1):54-7. [Content Brief]
- [2]. Dikalov SI, et al. Amyloid beta peptides do not form peptide-derived free radicals spontaneously, but can enhance metal-catalyzed oxidation of hydroxylamines to nitroxides. J Biol Chem. 1999 Apr 2;274(14):9392-9. [Content Brief]
