404828-14-4
404828-14-4
Chemical Structure
GSK-3 Inhibitor XIII
- CAS No.: 404828-14-4
- Formula:C18H15N5
- Molecular Weight:301.35
IUPAC Name: N-(5-methyl-1H-pyrazol-3-yl)-2-phenylquinazolin-4-amine
InChIKey: JYCUVOXSZBECAY-UHFFFAOYSA-N
SMILES: CC1=CC(NC2=C3C=CC=CC3=NC(C4=CC=CC=C4)=N2)=NN1
Biological Activity: GSK-3 Inhibitor XIII is a potent and ATP-competitive GSK-3 inhibitor with a Ki of 24 nM[1][1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
GSK-3 Inhibitor XIII | 98.79% | GSK-3 Inhibitor XIII is a potent and ATP-competitive GSK-3 inhibitor with a Ki of 24 nM. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Albert C Pierce, et al. CH...O and CH...N hydrogen bonds in ligand design: a novel quinazolin-4-ylthiazol-2-ylamine protein kinase inhibitor. J Med Chem. 2005 Feb 24;48(4):1278-81. [Content Brief]
- [2]. Eduardo Cruz Moraes, et al. Kinase inhibitor profile for human nek1, nek6, and nek7 and analysis of the structural basis for inhibitor specificity. Molecules. 2015 Jan 13;20(1):1176-91. [Content Brief]
Keywords
