439579-22-3
Chemical Structure
5-Bromo-3’-deoxy-3’-fluorouridine
- CAS No.: 439579-22-3
- Formula:C9H10BrFN2O5
- Molecular Weight:325.09
IUPAC Name: 5-bromo-1-((2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
InChIKey: ICQANOOKDZLVDM-UAKXSSHOSA-N
SMILES: OC[C@@H]1[C@@H](F)[C@@H](O)[C@H](N2C(NC(C(Br)=C2)=O)=O)O1
Biological Activity: 5-Bromo-3’-deoxy-3’-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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5-Bromo-3’-deoxy-3’-fluorouridine | 5-Bromo-3’-deoxy-3’-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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Keywords
