460346-02-5
460346-02-5
Chemical Structure
P7-2104
- CAS No.: 460346-02-5
- Formula:C14H17ClN2O2
- Molecular Weight:280.75
IUPAC Name: 8'-chloro-5'-methoxy-1'H-spiro[cyclohexane-1,4'-quinazolin]-2'(3'H)-one
InChIKey: CVJGVQVPEASPCK-UHFFFAOYSA-N
SMILES: O=C(N1)NC2=C(C31CCCCC3)C(OC)=CC=C2Cl
Biological Activity: P7-2104 is a blood-brain barrier-permeable, selective PDE7A inhibitor with an IC50 of 31 nM. P7-2104 shows selectivity for hERG channels and most CYP450 subtypes. P7-2104 can be used for PDE7-targeted PET neuroimaging studies and research related to neurodegenerative diseases, when labeled with 11C or 18F[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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P7-2104 | 99.77% | P7-2104 is a blood-brain barrier-permeable, selective PDE7A inhibitor with an IC50 of 31 nM. P7-2104 shows selectivity for hERG channels and most CYP450 subtypes. P7-2104 can be used for PDE7-targeted PET neuroimaging studies and research related to neurodegenerative diseases, when labeled with 11C or 18F. | ||||||||||||||||||||
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References
Keywords
