461449-78-5
461449-78-5
Chemical Structure
MRK-623
- CAS No.: 461449-78-5
- Formula:C20H17FN4O
- Molecular Weight:348.37
IUPAC Name: 2-(3-(4-fluoro-3-(pyridin-3-yl)phenyl)imidazo[1,2-a]pyrimidin-7-yl)propan-2-ol
InChIKey: GFQMHVYMEKXHDT-UHFFFAOYSA-N
SMILES: CC(O)(C1=NC2=NC=C(C3=CC=C(F)C(C4=CC=CN=C4)=C3)N2C=C1)C
Biological Activity: MRK-623 (Compound 14k) is an orally active, high-affinity GABAA receptor agonist, with the Ki values of 0.85 nM, 3.7 nM, 4.0 nM, and 0.53 nM for α1, α2, α3, and α5, respectively. MRK-623 shows anxiolytic effect[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MRK-623 | 98.73% | MRK-623 (Compound 14k) is an orally active, high-affinity GABAA receptor agonist, with the Ki values of 0.85 nM, 3.7 nM, 4.0 nM, and 0.53 nM for α1, α2, α3, and α5, respectively. MRK-623 shows anxiolytic effect. | ||||||||||||||||||||
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References
Keywords
