501000-36-8
501000-36-8
Chemical Structure
Dutacatib
- CAS No.: 501000-36-8
- Formula:C23H31N7O
- Molecular Weight:421.54
IUPAC Name: N-((2-cyano-4-(neopentylamino)pyrimidin-5-yl)methyl)-4-(4-methylpiperazin-1-yl)benzamide
InChIKey: IRWDVLZZYSYUAI-UHFFFAOYSA-N
SMILES: O=C(NCC1=CN=C(C#N)N=C1NCC(C)(C)C)C2=CC=C(N3CCN(C)CC3)C=C2
Biological Activity: Dutacatib is inhibitor for SARS-CoV-2 3CLpro and cathepsin K, which exhibits antiviral activity and ameliorates the cancer-induced bone diseases[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Dutacatib | Dutacatib is inhibitor for SARS-CoV-2 3CLpro and cathepsin K, which exhibits antiviral activity and ameliorates the cancer-induced bone diseases. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Sousa S, et al., Bone-Targeted Therapies in Cancer-Induced Bone Disease. Calcif Tissue Int. 2018 Feb;102(2):227-250. [Content Brief]
- [2]. Dayan Elshan NGR, et al., Discovery of CMX990: A Potent SARS-CoV-2 3CL Protease Inhibitor Bearing a Novel Warhead. J Med Chem. 2024 Feb 22;67(4):2369-2378. [Content Brief]
Keywords
