509118-03-0
509118-03-0
Chemical Structure
ATC0175 free base
- CAS No.: 509118-03-0
- Formula:C23H25F2N5O
- Molecular Weight:425.47
IUPAC Name: N-((1s,4s)-4-((4-(dimethylamino)quinazolin-2-yl)amino)cyclohexyl)-3,4-difluorobenzamide
InChIKey: FAIMGWSOSCFGRU-IYBDPMFKSA-N
SMILES: CN(C1=NC(N[C@H]2CC[C@H](CC2)NC(C3=CC(F)=C(C=C3)F)=O)=NC4=C1C=CC=C4)C
Biological Activity: ATC0175 (free base) is a potent and selective antagonist of melanin-concentrating hormone receptor 1 (MCH-R1) with an IC50 value of 3.4 nM, as well as good selectivity over the Y5 and the α2A receptors. ATC0175 (free base) is promising for research of obesity[1].
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ATC0175 free base | ATC0175 (free base) is a potent and selective antagonist of melanin-concentrating hormone receptor 1 (MCH-R1) with an IC50 value of 3.4 nM, as well as good selectivity over the Y5 and the α2A receptors. ATC0175 (free base) is promising for research of obesity. | |||||||||||||||||||||
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References
Keywords
