518-29-6
Chemical Structure
(-)-β-Peltatin
Synonym(s): β-Peltatin
- CAS No.: 518-29-6
- Formula:C22H22O8
- Molecular Weight:414.41
IUPAC Name: (5R,5aR,8aR)-10-hydroxy-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one
InChIKey: HLBPOYVRLSXWJJ-PDSMFRHLSA-N
SMILES: O=C1[C@]2([H])[C@H](C3=CC(OC)=C(C(OC)=C3)OC)C4=CC(OCO5)=C5C(O)=C4C[C@@]2([H])CO1
Biological Activity: (-)-β-Peltatin is an aryltetrahydronaphthalene lignan. (-)-β-Peltatin exhibits antitumor activity and cytotoxicity against pancreatic cancer cells. (-)-β-Peltatin induces G2/M cell cycle arrest and apoptosis in pancreatic cancer cells. (-)-β-Peltatin inhibits the growth of subcutaneous xenografts of pancreatic cancer cells in nude mice. (-)-β-Peltatin can be used in pancreatic cancer-related research[1][2].
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(-)-β-Peltatin | 99.45% | (-)-β-Peltatin is an aryltetrahydronaphthalene lignan. (-)-β-Peltatin exhibits antitumor activity and cytotoxicity against pancreatic cancer cells. (-)-β-Peltatin induces G2/M cell cycle arrest and apoptosis in pancreatic cancer cells. (-)-β-Peltatin inhibits the growth of subcutaneous xenografts of pancreatic cancer cells in nude mice. (-)-β-Peltatin can be used in pancreatic cancer-related research. | ||||||||||||||||||||
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- [1]. WIDAD M. KAMIL, et al. BIOSYNTHESIS OF THE LIGNANS cx-AND /3-PELTATIN. Phytochemistry, Vol. 25, No. 9, pp. 2089-2092, 1986.
- [2]. Wu R, et al. Pulsatilla Decoction and its bioactive component β-peltatin induce G2/M cell cycle arrest and apoptosis in pancreatic cancer. Chin Med. 2023;18(1):61. Published 2023 May 28. [Content Brief]
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