52417-22-8
52417-22-8
Chemical Structure
Acridin-9-amine hydrochloride hydrate
- CAS No.: 52417-22-8
- Formula:C13H13ClN2O
- Molecular Weight:248.71
IUPAC Name: acridin-9(10H)-imine hydrochloride hydrate
InChIKey: OREJEGKBQBIJSJ-UHFFFAOYSA-N
SMILES: N=C1C2=CC=CC=C2NC3=CC=CC=C31.Cl.O
Biological Activity: Acridin-9-amine (9-Aminoacridine) hydrochloride hydrate is a mutagen and DNA modifier. Acridin-9-amine hydrochloride hydrate induces mutagenic lesions during DNA replication[1][2].
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Acridin-9-amine hydrochloride hydrate | Acridin-9-amine (9-Aminoacridine) hydrochloride hydrate is a mutagen and DNA modifier. Acridin-9-amine hydrochloride hydrate induces mutagenic lesions during DNA replication. | |||||||||||||||||||||
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References
- [1]. Ferguson LR, et al. Comparative studies of mutagenic, DNA binding and antileukaemic properties of 9-anilinoacridine derivatives and related compounds. Chem Biol Interact. 1983 Apr-May;44(1-2):53-62. [Content Brief]
- [2]. Conrad M, et al. Induction of deletion and insertion mutations by 9-aminoacridine. An in vitro model. J Biol Chem. 1986 Dec 5;261(34):16226-32. [Content Brief]
