52691-24-4
52691-24-4
Chemical Structure
Dichloro(1,2-diaminocyclohexane)platinum(II)
- CAS No.: 52691-24-4
- Formula:C6H14Cl2N2Pt
- Molecular Weight:380.18
IUPAC Name: (1R,2S)-2-(aminomethyl)cyclohexan-1-ol hydrochloride
InChIKey: PNNCIXRVXCLADM-UHFFFAOYSA-L
SMILES: [Cl-][Pt+2]1([NH2]C2CCCCC2[NH2]1)[Cl-]
Biological Activity: Dichloro(1,2-diaminocyclohexane)platinum(II) is a platinum (II) analog and the oxaliplatin parent complex. Dichloro(1,2-diaminocyclohexane)platinum(II) is a potent chemotherapeutic with a wide spectrum of anticancer activity, low toxicity, and lack of cross resistance in many cisplatin-resistant cancers[1].
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Dichloro(1,2-diaminocyclohexane)platinum(II) | Dichloro(1,2-diaminocyclohexane)platinum(II) is a platinum (II) analog and the oxaliplatin parent complex. Dichloro(1,2-diaminocyclohexane)platinum(II) is a potent chemotherapeutic with a wide spectrum of anticancer activity, low toxicity, and lack of cross resistance in many cisplatin-resistant cancers. | |||||||||||||||||||||
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References
- [1]. Oberoi HS, et al., (2011). Dichloro(1,2-Diaminocyclohexane)Platinum(II) (DACHPt) Loaded Polymer Micelles with Cross-Linked Core: Preparation and Characterization. PMSE preprints. American Chemical Society. Division of Polymeric Materials: Science and Engineering. Meeting, 104, 630–631. [Content Brief]
