565226-18-8
565226-18-8
Chemical Structure
3’,5’-Di-O-acetyl-2’-deoxy-2’-fluoro-5-iodouridine
- CAS No.: 565226-18-8
- Formula:C13H14FIN2O7
- Molecular Weight:456.16
IUPAC Name: ((2R,3R,4R,5R)-3-acetoxy-4-fluoro-5-(5-iodo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl acetate
InChIKey: NKKIVBSOBGMPNP-DNRKLUKYSA-N
SMILES: O=C(N1)N([C@H]2[C@H](F)[C@H](OC(C)=O)[C@@H](COC(C)=O)O2)C=C(I)C1=O
Biological Activity: 3’,5’-Di-O-acetyl-2’-deoxy-2’-fluoro-5-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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3’,5’-Di-O-acetyl-2’-deoxy-2’-fluoro-5-iodouridine | 3’,5’-Di-O-acetyl-2’-deoxy-2’-fluoro-5-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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