59000-66-7
Chemical Structure
Cholestanol stearate
- CAS No.: 59000-66-7
- Formula:C45H82O2
- Molecular Weight:655.13
InChIKey: LBRZDDGANDHILT-GVZMFZCXSA-N
SMILES: C[C@@]12[C@]3([H])[C@](CC[C@@]1([H])C[C@H](CC2)OC(CCCCCCCCCCCCCCCCC)=O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCCC(C)C)C
Biological Activity: Cholestanol stearate serves as a substrate for plasma lecithin:cholesterol acyltransferase (LCAT), with an esterification rate of approximately 70% that of cholesterol. Cholestanol stearate contains both hydrophilic and lipophilic groups, and its components are related to the structural substances of natural products. Cholestanol stearate can be used in studies related to cerebrotendinous xanthomatosis and familial lecithin:cholesterol acyltransferase deficiency[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Cholestanol stearate | Cholestanol stearate serves as a substrate for plasma lecithin:cholesterol acyltransferase (LCAT), with an esterification rate of approximately 70% that of cholesterol. Cholestanol stearate contains both hydrophilic and lipophilic groups, and its components are related to the structural substances of natural products. Cholestanol stearate can be used in studies related to cerebrotendinous xanthomatosis and familial lecithin:cholesterol acyltransferase deficiency. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. North BE, et al. The thermal transitions and structural properties of 5alpha-cholestan-3beta-ol esters of aliphatic acids. Biochim Biophys Acta. 1976 Mar 26;424(3):376-85.
- [2]. Matsumoto Y, et al. Cholestanol esters of amino acids. Bull Chem Soc Jpn. 1967 Jul;40(7):1650-5.
- [3]. Skrede S, et al. Plasma esterification of cholestanol, normally and in cerebrotendinous xanthomatosis. Scand J Clin Lab Invest. 1974 Apr;33(2):97-100.
