621-42-1
Chemical Structure
Metacetamol
Synonym(s): AMAP
- CAS No.: 621-42-1
- Formula:C8H9NO2
- Molecular Weight:151.16
IUPAC Name: N-(3-hydroxyphenyl)acetamide
InChIKey: QLNWXBAGRTUKKI-UHFFFAOYSA-N
SMILES: CC(NC1=CC=CC(O)=C1)=O
Biological Activity: Metacetamol (AMAP) is an analog of Acetaminophen (HY-66005). Metacetamol induces dose-dependent necrosis in primary hepatocytes via glutathione depletion, mitochondrial damage, and formation of mitochondrial protein adducts. Metacetamol derivatives act as anticancer and antibacterial agents. Metacetamol can be used in studies related to breast cancer, bacterial infections, and fungal infections (candidiasis)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Metacetamol | 99.94% | Metacetamol (AMAP) is an analog of Acetaminophen (HY-66005). Metacetamol induces dose-dependent necrosis in primary hepatocytes via glutathione depletion, mitochondrial damage, and formation of mitochondrial protein adducts. Metacetamol derivatives act as anticancer and antibacterial agents. Metacetamol can be used in studies related to breast cancer, bacterial infections, and fungal infections (candidiasis). | ||||||||||||||||||||
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- [1]. Xie Y, et al. Mitochondrial protein adducts formation and mitochondrial dysfunction during N-acetyl-m-aminophenol (AMAP)-induced hepatotoxicity in primary human hepatocytes. Toxicol Appl Pharmacol. 2015;289(2):213-222. [Content Brief]
- [2]. Şenkardeş S, et al. Synthesis and Evaluation of Novel Metacetamol Derivatives with Hydrazone Moiety as Anticancer and Antimicrobial Agents. Chem Biodivers. 2023;20(8):e202300766. [Content Brief]
Keywords
