661470-65-1
661470-65-1
Chemical Structure
3’-Deoxy-3’,5-difluorocytidine
- CAS No.: 661470-65-1
- Formula:C9H11F2N3O4
- Molecular Weight:263.20
IUPAC Name: 4-amino-5-fluoro-1-((2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
InChIKey: KHGOGZGLQQVORD-UAKXSSHOSA-N
SMILES: F[C@H]1[C@@H](O)[C@H](N2C=C(F)C(N)=NC2=O)O[C@@H]1CO
Biological Activity: 3’-Deoxy-3’,5-difluorocytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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3’-Deoxy-3’,5-difluorocytidine | 3’-Deoxy-3’,5-difluorocytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
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