66389-74-0
66389-74-0
Chemical Structure
(+)-Apogossypol
Synonym(s): Apogossypol; NSC736630
- CAS No.: 66389-74-0
- Formula:C28H32O6
- Molecular Weight:462.54
IUPAC Name: (S)-5,5'-diisopropyl-3,3'-dimethyl-[2,2'-binaphthalene]-1,1',6,6',7,7'-hexaol compound with hydrogen sulfide (1:1)
InChIKey: MEOWTYRKWJLKKQ-UHFFFAOYSA-N
SMILES: OC1=C2C=C(O)C(O)=C(C(C)C)C2=CC(C)=[C@@]1[C@@]3=C(C)C=C4C(C(C)C)=C(O)C(O)=CC4=C3O
Biological Activity: (+)-Apogossypol is a pan-BCL-2 antagonist. (+)-Apogossypol binds to Mcl-1, Bcl-2 and Bcl-xL with EC50s of 2.6, 2.8 and 3.69 µM, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
(+)-Apogossypol | (+)-Apogossypol is a pan-BCL-2 antagonist. (+)-Apogossypol binds to Mcl-1, Bcl-2 and Bcl-xL with EC50s of 2.6, 2.8 and 3.69 µM, respectively. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
