690271-27-3
Chemical Structure
2’,3’-Di-O-isopropylidene-4’-alpha-C-azidouridine
- CAS No.: 690271-27-3
- Formula:C12H15N5O6
- Molecular Weight:325.28
IUPAC Name: 1-((3aR,4R,6R,6aS)-6-azido-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)pyrimidine-2,4(1H,3H)-dione
InChIKey: HTFJMKYZSCAXLC-JXVAYASWSA-N
SMILES: O=C(NC1=O)C=CN1[C@H](O2)[C@H]3[C@H](OC(C)(C)O3)[C@]2(CO)N=[N+]=[N-]
Biological Activity: 2’,3’-Di-O-isopropylidene-4’-alpha-C-azidouridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1]. 2’,3’-Di-O-isopropylidene-4’-alpha-C-azidouridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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2’,3’-Di-O-isopropylidene-4’-alpha-C-azidouridine | 2’,3’-Di-O-isopropylidene-4’-alpha-C-azidouridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents. 2’,3’-Di-O-isopropylidene-4’-alpha-C-azidouridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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