725223-44-9
Chemical Structure
Rev 2’-O-MOE-G(iBu)-5’-amidite
- CAS No.: 725223-44-9
- Formula:C47H60N7O10P
- Molecular Weight:913.99
IUPAC Name: ((2R,3R,4R,5R)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(2-methoxyethoxy)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite
InChIKey: YLDSIMQFLQLTEA-SBCRAQIVSA-N
SMILES: O=C1C2=C(N([C@H]3[C@H](OCCOC)[C@H](OC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)[C@@H](COP(N(C(C)C)C(C)C)OCCC#N)O3)C=N2)N=C(NC(C(C)C)=O)N1
Biological Activity: Rev 2’-O-MOE-G(iBu)-5’-amidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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Rev 2’-O-MOE-G(iBu)-5’-amidite | Rev 2’-O-MOE-G(iBu)-5’-amidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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Keywords
