771467-00-6
771467-00-6
Chemical Structure
PKM2-IN-6
- CAS No.: 771467-00-6
- Formula:C17H14N4OS
- Molecular Weight:322.38
InChIKey: XRKBXMDFJSWCQP-UHFFFAOYSA-N
SMILES: COC1=CC=CC=C1NC2=NC(C3=CN=C4C=CC=CN43)=CS2
Biological Activity: PKM2-IN-6 (compound 7d) is a potent and orally active PKM2 inhibitor with an IC50 value of 23 nM. PKM2-IN-6 induces apoptosis and cell cycle arrest at G2 phase. PKM2-IN-6 reduces the level of PKM1 and PKM2 at the mRNA level. PKM2-IN-6 shows anticancer activity and has the potential for the research of triple-negative breast cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PKM2-IN-6 | 99.95% | PKM2-IN-6 (compound 7d) is a potent and orally active PKM2 inhibitor with an IC50 value of 23 nM. PKM2-IN-6 induces apoptosis and cell cycle arrest at G2 phase. PKM2-IN-6 reduces the level of PKM1 and PKM2 at the mRNA level. PKM2-IN-6 shows anticancer activity and has the potential for the research of triple-negative breast cancer. | ||||||||||||||||||||
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References
Keywords
