83546-42-3
83546-42-3
Chemical Structure
1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione
- CAS No.: 83546-42-3
- Formula:C11H15FN2O5
- Molecular Weight:274.25
IUPAC Name: 5-ethyl-1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
InChIKey: SWFJAJRDLUUIOA-IBCQBUCCSA-N
SMILES: O[C@H]1[C@H](F)[C@H](N(C(N2)=O)C=C(CC)C2=O)O[C@@H]1CO
Biological Activity: 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].
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1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione | 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis. | |||||||||||||||||||||
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References
