85280-91-7
Chemical Structure
17-Phenyl-18,19,20-trinor-PGD2
Synonym(s): 17-Phenyl-PGD2
- CAS No.: 85280-91-7
- Formula:C23H30O5
- Molecular Weight:386.48
IUPAC Name: (Z)-7-((1R,2R,5S)-5-hydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)-3-oxocyclopentyl)hept-5-enoic acid
InChIKey: OAQGPAZDRCBBLD-YTCWWFNZSA-N
SMILES: OC(CCC/C=C\C[C@@H]1[C@H](C(C[C@@H]1O)=O)/C=C/[C@@H](O)CCC2=CC=CC=C2)=O
Biological Activity: 17-Phenyl-18,19,20-trinor-PGD2 (17-Phenyl-PGD2) is an analogue of prostaglandin D2 (PGD2; HY-101988). 17-Phenyl-18,19,20-trinor-PGD2 is a potent inhibitor of platelet aggregation caused by aenosine diphosphate (ADP), with the IC50 of 8.4 μM (PGD2 IC50 = 18.6 nM). 17-Phenyl-18,19,20-trinor-PGD2 is a weak agonist of cyclic AMP accumulation[1].
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17-Phenyl-18,19,20-trinor-PGD2 | 17-Phenyl-18,19,20-trinor-PGD2 (17-Phenyl-PGD2) is an analogue of prostaglandin D2 (PGD2; HY-101988). 17-Phenyl-18,19,20-trinor-PGD2 is a potent inhibitor of platelet aggregation caused by aenosine diphosphate (ADP), with the IC50 of 8.4 μM (PGD2 IC50 = 18.6 nM). 17-Phenyl-18,19,20-trinor-PGD2 is a weak agonist of cyclic AMP accumulation. | |||||||||||||||||||||
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Keywords
