857665-72-6
857665-72-6
Chemical Structure
3-Chloro-L-tyrosine-13C6
- CAS No.: 857665-72-6
- Formula:C313C6H10ClNO3
- Molecular Weight:221.59
IUPAC Name: tert-butyl 4-(5-ethynylpyridin-2-yl)piperazine-1-carboxylate
InChIKey: ACWBBAGYTKWBCD-DXQQUZLMSA-N
SMILES: OC([C@H](C[13C]1=[13CH][13C](Cl)=[13C](O)[13CH]=[13CH]1)N)=O
Biological Activity: 3-Chloro-L-tyrosine-13C6 is the 13C labeled 3-Chloro-L-tyrosine[1]. 3-Chloro-L-tyrosine is a specific marker of myeloperoxidase-catalyzed oxidation, and is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima[2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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3-Chloro-L-tyrosine-13C6 | 97.6% | 3-Chloro-L-tyrosine-13C6 is the 13C labeled 3-Chloro-L-tyrosine. 3-Chloro-L-tyrosine is a specific marker of myeloperoxidase-catalyzed oxidation, and is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. Hazen SL, et al. 3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima. J Clin Invest. 1997 May 1;99(9):2075-81. [Content Brief]
Keywords
