86137-72-6
Chemical Structure
2’-Deoxy-O6-[2-(4-nitrophenylethyl)]guanosine
- CAS No.: 86137-72-6
- Formula:C18H20N6O6
- Molecular Weight:416.39
IUPAC Name: (2R,3S,5R)-5-(2-amino-6-(4-nitrophenethoxy)-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol
InChIKey: BJWXZOBLBMGQCJ-BFHYXJOUSA-N
SMILES: OC[C@@H]1[C@@H](O)C[C@H](N2C=NC3=C2N=C(N)N=C3OCCC4=CC=C([N+]([O-])=O)C=C4)O1
Biological Activity: 2’-Deoxy-O6-[2-(4-nitrophenylethyl)]guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2’-Deoxy-O6-[2-(4-nitrophenylethyl)]guanosine | 2’-Deoxy-O6-[2-(4-nitrophenylethyl)]guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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