864374-00-5
864374-00-5
Chemical Structure
TP0427736
- CAS No.: 864374-00-5
- Formula:C14H10N4S2
- Molecular Weight:298.39
IUPAC Name: 6-(4-(4-methylthiazol-2-yl)-1H-imidazol-5-yl)benzo[d]thiazole
InChIKey: LLFCXRYULHMNCG-UHFFFAOYSA-N
SMILES: CC1=CSC(C2=C(NC=N2)C3=CC=C4N=CSC4=C3)=N1
Biological Activity: TP0427736 is a selective inhibitor of ALK5 with an IC50 of 2.72 nM. TP0427736 inhibits Smad2/3 phosphorylation in A549 cells. TP0427736 decreases the growth inhibition of human outer root sheath cells[1].
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TP0427736 | TP0427736 is a selective inhibitor of ALK5 with an IC50 of 2.72 nM. TP0427736 inhibits Smad2/3 phosphorylation in A549 cells. TP0427736 decreases the growth inhibition of human outer root sheath cells. | |||||||||||||||||||||
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References
Keywords
