872178-65-9
Chemical Structure
Rabeximod
Synonym(s): ROB-803
- CAS No.: 872178-65-9
- Formula:C22H24ClN5O
- Molecular Weight:409.91
IUPAC Name: 2-(9-chloro-2,3-dimethyl-6H-indolo[2,3-b]quinoxalin-6-yl)-N-(2-(dimethylamino)ethyl)acetamide
InChIKey: PDNNUMNEXITLCZ-UHFFFAOYSA-N
SMILES: O=C(CN1C2=NC3=C(N=C2C4=C1C=CC(Cl)=C4)C=C(C)C(C)=C3)NCCN(C)C
Biological Activity: Rabeximod (ROB-803), an anti-rheumatic compound, impairs the differentiation and function of human pro-inflammatory dendritic cells and macrophages via downregulating TLR2 and TLR4 stimulation. Rabeximod (ROB-803) is used for rheumatoid arthritis (RA) research[1].
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Rabeximod | Rabeximod (ROB-803), an anti-rheumatic compound, impairs the differentiation and function of human pro-inflammatory dendritic cells and macrophages via downregulating TLR2 and TLR4 stimulation. Rabeximod (ROB-803) is used for rheumatoid arthritis (RA) research. | |||||||||||||||||||||
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Keywords