878006-06-5
![(E)-[6]-Dehydroparadol Chemical Structure](http://file.medchemexpress.cn/product_pic/hy-77293.gif "(E)-[6]-Dehydroparadol Chemical Structure")
878006-06-5
Chemical Structure
(E)-[6]-Dehydroparadol
- CAS 番号: 878006-06-5
- Formula:C17H24O3
- Molecular Weight:276.37
IUPAC Name: (E)-1-(4-hydroxy-3-methoxyphenyl)dec-1-en-3-one
InChIKey: AXMBOMODZLJDKX-PKNBQFBNSA-N
SMILES: CCCCCCCC(/C=C/C1=CC=C(O)C(OC)=C1)=O
Biological Activity: (E)-[6]-Dehydroparadol, an oxidative metabolite of [6]-Shogaol (HY-14616), is a potent Nrf2 activator. (E)-[6]-Dehydroparadol can inhibit the growth and induce the apoptosis of human cancer cells[1][2].
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(E)-[6]-Dehydroparadol | 95.0% | (E)--Dehydroparadol, an oxidative metabolite of -Shogaol (HY-14616), is a potent Nrf2 activator. (E)--Dehydroparadol can inhibit the growth and induce the apoptosis of human cancer cells. | ||||||||||||||||||||
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References
- [1]. Chen H, et, al. Metabolism of ginger component [6]-shogaol in liver microsomes from mouse, rat, dog, monkey, and human. Mol Nutr Food Res. 2013 May;57(5):865-76. [Content Brief]
- [2]. Zhu Y, et, al. Synthesis, evaluation, and metabolism of novel [6]-shogaol derivatives as potent Nrf2 activators. Free Radic Biol Med. 2016 Jun;95:243-54. [Content Brief]
Keywords
