885672-81-1
885672-81-1
Chemical Structure
FL104
- CAS No.: 885672-81-1
- Formula:C24H25ClN2O
- Molecular Weight:392.92
IUPAC Name: N-(1-(4-chlorophenyl)-3-(dimethylamino)propyl)-[1,1'-biphenyl]-4-carboxamide
InChIKey: JXJCJZNVWYQHIF-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(C2=CC=CC=C2)C=C1)NC(CCN(C)C)C3=CC=C(C=C3)Cl
Biological Activity: FL104 is a potent small molecule urotensin II receptor agonist with pEC50 of 7.11 for UTII receptor in R-SATTM assay[1][2].
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FL104 | FL104 is a potent small molecule urotensin II receptor agonist with pEC50 of 7.11 for UTII receptor in R-SATTM assay. | |||||||||||||||||||||
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References
- [1]. Lehmann F, et al. Novel and potent small-molecule urotensin II receptor agonists. Bioorg Med Chem. 2009 Jul 1;17(13):4657-65. [Content Brief]
- [2]. Lehmann F, et al. Design, parallel synthesis and SAR of novel urotensin II receptor agonists. Eur J Med Chem. 2007 Feb;42(2):276-85. [Content Brief]
Keywords
