885896-54-8
Chemical Structure
PSB-KK1445
- CAS No.: 885896-54-8
- Formula:C24H23FN6O2
- Molecular Weight:446.48
InChIKey: JMZXYZSTEKMPDV-UHFFFAOYSA-N
SMILES: CN1C2=C(C(N(C1=O)C)=O)N(C(NCCC3=CNC4=C3C=CC=C4)=N2)CC5=CC=C(C=C5)F
Biological Activity: PSB-KK1445 is a potent and selective GPR18 agonist with EC50s of 45.4 nM and 124 nM for human and mouse GPR18, respectively. PSB-KK1445 displays >200-fold selectivity versus both CB receptor subtypes, GPR55, and GPR183[1].
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PSB-KK1445 | 99.80% | PSB-KK1445 is a potent and selective GPR18 agonist with EC50s of 45.4 nM and 124 nM for human and mouse GPR18, respectively. PSB-KK1445 displays >200-fold selectivity versus both CB receptor subtypes, GPR55, and GPR183. | ||||||||||||||||||||
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Keywords