89845-82-9
Chemical Structure
2',3'-O-Isopropylidene-5-pyrrolidinomethyl-2-thiouridine
- CAS No.: 89845-82-9
- Formula:C17H25N3O5S
- Molecular Weight:383.46
IUPAC Name: 1-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-5-(pyrrolidin-1-ylmethyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
InChIKey: IFJTVPASSJKUFD-RGCMKSIDSA-N
SMILES: O=C(C(CN1CCCC1)=C2)NC(N2[C@@H]3O[C@H](CO)[C@@H]4[C@H]3OC(C)(C)O4)=S
Biological Activity: 2',3'-O-Isopropylidene-5-pyrrolidinomethyl-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2',3'-O-Isopropylidene-5-pyrrolidinomethyl-2-thiouridine | 2',3'-O-Isopropylidene-5-pyrrolidinomethyl-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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