89947-86-4
Chemical Structure
3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine
- CAS No.: 89947-86-4
- Formula:C37H45N5O5Si
- Molecular Weight:667.87
IUPAC Name: 9-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-2-yl)-9H-purin-6-amine
InChIKey: BLILIIKIHHYPLG-DCMFLLSESA-N
SMILES: NC1=NC=NC2=C1N=CN2[C@@H]3O[C@H](COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)[C@@H](O[Si](C)(C)C(C)(C)C)C3
Biological Activity: 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine | 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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