899827-82-8
899827-82-8
Chemical Structure
2-Hydroxy-2’-deoxy-2’-fluoro-beta-D-arabino adenosine
- CAS No.: 899827-82-8
- Formula:C10H12FN5O4
- Molecular Weight:285.23
IUPAC Name: 6-amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purin-2-one
InChIKey: SRUXNNJIKBFXNW-AYQXTPAHSA-N
SMILES: O[C@H]1[C@H](F)[C@H](N(C=N2)C3=C2C(N)=NC(N3)=O)O[C@@H]1CO
Biological Activity: 2-Hydroxy-2’-de oxy-2’-fluoro-beta-D-arabino adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2-Hydroxy-2’-deoxy-2’-fluoro-beta-D-arabino adenosine | 2-Hydroxy-2’-de oxy-2’-fluoro-beta-D-arabino adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
