1 Result for "

914302-78-6

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "914302-78-6" in MCE Product Catalog:

Cat. No.: HY-181960
CAS No.: 914302-78-6
Target:  

Histamine Receptor

Research Areas:  

Neurological Disease

BP1.3656B is a selective, orally active, blood-brain barrier-permeable histamine H3 receptor (histamine H3 receptor) inverse agonist/antagonist, with a KB value of 0.08 nM for antagonizing agonist-induced activity and an IC50 value of 0.38 nM for directly inhibiting the basal activity of the receptor. BP1.3656B reduces alcohol consumption, alcohol-seeking behavior, alcohol self-administration, motivation to drink, alcohol relapse, alcohol-induced hyperlocomotion, and binge alcohol intake. BP1.3656B is applicable for the research of alcohol use disorder .
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