915942-22-2
915942-22-2
Chemical Structure
Neratinib maleate
Synonym(s): HKI-272 maleate
- CAS No.: 915942-22-2
- Formula:C34H33ClN6O7
- Molecular Weight:673.11
IUPAC Name: (E)-N-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide maleate
InChIKey: VXZCUHNJXSIJIM-MEBGWEOYSA-N
SMILES: OC(/C=C\C(O)=O)=O.CCOC(C(NC(/C=C/CN(C)C)=O)=C1)=CC2=C1C(NC3=CC(Cl)=C(C=C3)OCC4=CC=CC=N4)=C(C#N)C=N2
Biological Activity: Neratinib (HKI-272) maleate is an orally available, irreversible, highly selective HER2 and EGFR inhibitor with IC50s of 59 nM and 92 nM, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Neratinib maleate | 99.74% | Neratinib (HKI-272) maleate is an orally available, irreversible, highly selective HER2 and EGFR inhibitor with IC50s of 59 nM and 92 nM, respectively. | ||||||||||||||||||||
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References
Keywords
