916046-55-4

CRTh2 antagonist 4 Chemical Structure
916046-55-4

Chemical Structure

CRTh2 antagonist 4

  • CAS No.: 916046-55-4
  • Formula:C20H14ClFN2O5
  • Molecular Weight:416.79

IUPAC Name: 2-(5-chloro-1'-(2-fluorobenzyl)-2,2',5'-trioxospiro[indoline-3,3'-pyrrolidin]-1-yl)acetic acid

InChIKey: SKLDVYDFQCXARY-UHFFFAOYSA-N

SMILES: O=C(O)CN1C(C2(C(N(CC3=CC=CC=C3F)C(C2)=O)=O)C4=C1C=CC(Cl)=C4)=O

Biological Activity: CRTh2 antagonist 4 (compound 58) is an inhibitor (IC50: 212 nM) of TH2 lymphocyte (CRTH2 or DP2) receptor with high binding affinity (Ki= 37 nM). CRTh2 antagonist 4 can be used in the study of severe allergic diseases[1].

Cat. No. Product Name Purity Description Pricing
HY-116890 		CRTh2 antagonist 4 CRTh2 antagonist 4 (compound 58) is an inhibitor (IC50: 212 nM) of TH2 lymphocyte (CRTH2 or DP2) receptor with high binding affinity (Ki= 37 nM). CRTh2 antagonist 4 can be used in the study of severe allergic diseases.
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