916489-36-6
916489-36-6
Chemical Structure
MS417
Synonym(s): GTPL7512
- CAS No.: 916489-36-6
- Formula:C20H19ClN4O2S
- Molecular Weight:414.91
IUPAC Name: methyl (S)-2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate
InChIKey: GGRCIHACOIMRKY-HNNXBMFYSA-N
SMILES: O=C(OC)C[C@H]1C2=NN=C(C)N2C3=C(C(C)=C(C)S3)C(C4=CC=C(Cl)C=C4)=N1
Biological Activity: MS417 is a selective BET-specific BRD4 inhibitor, binds to BRD4-BD1 and BRD4-BD2 with IC50s of 30, 46 nM and Kds of 36.1, 25.4 nM, respectively, with weak selectivity at CBP BRD (IC50, 32.7 μM).
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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MS417 | 99.79% | MS417 is a selective BET-specific BRD4 inhibitor, binds to BRD4-BD1 and BRD4-BD2 with IC50s of 30, 46 nM and Kds of 36.1, 25.4 nM, respectively, with weak selectivity at CBP BRD (IC50, 32.7 μM). | ||||||||||||||||||||
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Keywords
