92214-56-7
Chemical Structure
Phorbol 12-tiglate
- CAS No.: 92214-56-7
- Formula:C25H34O7
- Molecular Weight:446.53
IUPAC Name: (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-4a,7b,9a-trihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yl (E)-2-methylbut-2-enoate
InChIKey: GHOKGLQIHWVNOK-AYDRJACZSA-N
SMILES: O[C@]12[C@](C2(C)C)([H])[C@@]3([H])[C@]([C@@H]([C@H]1OC(/C(C)=C/C)=O)C)([C@@]4([H])[C@](CC(CO)=C3)(C(C(C)=C4)=O)O)O
Biological Activity: Phorbol 12-tiglate is a derivative of Phorbol (HY-N2147). Phorbol, a hydrolyzed product of Croton oil, promotes tumor development by activating protein kinase C. Phorbol and its derivatives can be used to construct carcinogenic models in biomedical research[1].
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Phorbol 12-tiglate | Phorbol 12-tiglate is a derivative of Phorbol (HY-N2147). Phorbol, a hydrolyzed product of Croton oil, promotes tumor development by activating protein kinase C. Phorbol and its derivatives can be used to construct carcinogenic models in biomedical research. | |||||||||||||||||||||
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Keywords
