936449-28-4
936449-28-4
Chemical Structure
PDE5-IN-42
- CAS No.: 936449-28-4
- Formula:C23H31N7O3
- Molecular Weight:453.54
IUPAC Name: 1-(1-(2-ethoxyethyl)-3-ethyl-7-((4-methylpyridin-2-yl)amino)-1H-pyrazolo[4,3-d]pyrimidin-5-yl)piperidine-4-carboxylic acid
InChIKey: IQZQWPRZFLHJFI-UHFFFAOYSA-N
SMILES: O=C(C1CCN(C2=NC(NC3=NC=CC(C)=C3)=C(N(CCOCC)N=C4CC)C4=N2)CC1)O
Biological Activity: PDE5-IN-42 (Compound 42) is a potent and orally active PDE5 inhibitor with an IC50 of 0.04 nM. PDE5-IN-42 maintains selectivity over PDE6 and PDE11[1].
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PDE5-IN-42 | PDE5-IN-42 (Compound 42) is a potent and orally active PDE5 inhibitor with an IC50 of 0.04 nM. PDE5-IN-42 maintains selectivity over PDE6 and PDE11. | |||||||||||||||||||||
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References
Keywords
