937263-81-5
937263-81-5
Chemical Structure
ONT-993
Synonym(s): AR 00440993
- CAS No.: 937263-81-5
- Formula:C26H24N8O3
- Molecular Weight:496.52
IUPAC Name: (2-((4-((4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)amino)quinazolin-6-yl)amino)-4-methyl-4,5-dihydrooxazol-4-yl)methanol
InChIKey: TWEMIPSDKADNMC-UHFFFAOYSA-N
SMILES: OCC1(C)N=C(NC2=CC3=C(NC4=CC=C(C(C)=C4)OC5=CC6=NC=NN6C=C5)N=CN=C3C=C2)OC1
Biological Activity: ONT-993 is an aliphatic hydroxylated metabolite. ONT-993 inhibits CYP2D6 (IC50=7.9 µM) and causes metabolism-dependent inactivation of CYP3A (KI=1.6 µM)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ONT-993 | 99.85% | ONT-993 is an aliphatic hydroxylated metabolite. ONT-993 inhibits CYP2D6 (IC50=7.9 µM) and causes metabolism-dependent inactivation of CYP3A (KI=1.6 µM). | ||||||||||||||||||||
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References
Keywords
