94714-78-0
Chemical Structure
CGP 31523A
- CAS No.: 94714-78-0
- Formula:C16H15N7O5S4
- Molecular Weight:513.59
IUPAC Name: (6R,7R)-3-(((1,2,3-thiadiazol-5-yl)thio)methyl)-7-((S)-2-(2-aminothiazol-4-yl)-2-formamidoacetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
InChIKey: MLLOBKWZTXROPZ-IMSIIYSGSA-N
SMILES: OC(C1=C(CSC2=CN=NS2)CS[C@@]([C@@H]3NC([C@H](C4=CSC(N)=N4)NC=O)=O)([H])N1C3=O)=O
Biological Activity: CGP 31523A is a broad-spectrum aminothiazole cephalosporin. CGP 31523A exhibits potent inhibitory effects on Enterobacteriaceae, Neisseria, Haemophilus influenzae, and Streptococcus (except Enterococcus faecalis), among others. CGP 31523A can be hydrolyzed by the common Escherichia coli type Ic β-lactamase, but is stable against the Ia type enzyme. CGP 31523A is neither an effective β-lactamase inhibitor nor does it induce the production of β-lactamase. CGP 31523A can be used for studying infections caused by Gram-negative bacteria (including drug-resistant strains)[1].
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CGP 31523A | CGP 31523A is a broad-spectrum aminothiazole cephalosporin. CGP 31523A exhibits potent inhibitory effects on Enterobacteriaceae, Neisseria, Haemophilus influenzae, and Streptococcus (except Enterococcus faecalis), among others. CGP 31523A can be hydrolyzed by the common Escherichia coli type Ic β-lactamase, but is stable against the Ia type enzyme. CGP 31523A is neither an effective β-lactamase inhibitor nor does it induce the production of β-lactamase. CGP 31523A can be used for studying infections caused by Gram-negative bacteria (including drug-resistant strains). | |||||||||||||||||||||
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Keywords
