947303-87-9
947303-87-9
Chemical Structure
PF-429242
- CAS No.: 947303-87-9
- Formula:C25H35N3O2
- Molecular Weight:409.56
IUPAC Name: (R)-4-((diethylamino)methyl)-N-(2-methoxyphenethyl)-N-(pyrrolidin-3-yl)benzamide
InChIKey: XKPJTOHUPQWSOJ-HSZRJFAPSA-N
SMILES: O=C(N(CCC1=CC=CC=C1OC)[C@H]2CNCC2)C3=CC=C(CN(CC)CC)C=C3
Biological Activity: PF429242 is a reversible and competitive SREBP site 1 protease (S1P) inhibitor with an IC50 of 175 nM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PF-429242 | 99.59% | PF429242 is a reversible and competitive SREBP site 1 protease (S1P) inhibitor with an IC50 of 175 nM. | ||||||||||||||||||||
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References
- [1]. Hawkins JL, et al. Pharmacologic inhibition of site 1 protease activity inhibits sterol regulatory element-binding protein processing and reduces lipogenic enzyme gene expression and lipid synthesis in cultured cells and experimental animals. J Pharmacol Exp Ther. 2008 Sep;326(3):801-8. [Content Brief]
Keywords
