98774-41-5
98774-41-5
Chemical Structure
7α,25-Dihydroxy-4-cholesten-3-one
- CAS No.: 98774-41-5
- Formula:C27H44O3
- Molecular Weight:416.64
InChIKey: POUKDTOWHPHYQU-HENOKILYSA-N
SMILES: O=C(CC1)C=C(C[C@H]2O)[C@@]1(C)[C@]3([H])[C@]2([H])[C@@](CC[C@]4([H])[C@H](C)CCCC(C)(C)O)([H])[C@]4(C)CC3
Biological Activity: 7α,25-Dihydroxy-4-cholesten-3-one is a sterol metabolite. 25-Hydroxycholesterol is 7α-hydroxylated and further oxidized to 7α,25-Dihydroxy-4-cholesten-3-one[1].
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7α,25-Dihydroxy-4-cholesten-3-one | 7α,25-Dihydroxy-4-cholesten-3-one is a sterol metabolite. 25-Hydroxycholesterol is 7α-hydroxylated and further oxidized to 7α,25-Dihydroxy-4-cholesten-3-one. | |||||||||||||||||||||
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References
- [1]. Axelson M, et al. 27-hydroxylated low density lipoprotein (LDL) cholesterol can be converted to 7alpha,27-dihydroxy-4-cholesten-3-one (cytosterone) before suppressing cholesterol production in normal human fibroblasts. Evidence that an altered metabolism of ldl cholesterol can underlie a defective feedback control in malignant cells. J Biol Chem. 1996 May 31;271(22):12724-36. [Content Brief]
Keywords
