Catechin-5-O-gallate

Catechin-5-O-gallate binds to the active site of SARS-CoV-2 3CLpro (PDB ID: 6LU7) with a binding energy of -8.2 kcal/mol and a K_i of 0.99 μM, indicating its potential inhibitory activity against this viral protease^[1].
Catechin-5-O-gallate binds to the active site of SARS-CoV-2 PLpro (PDB ID: 7JRN) with a binding energy of -7.1 kcal/mol and a K_i of 6.34 μM, indicating its potential inhibitory activity against this viral protease^[1].
Catechin-5-O-gallate binds to the active site of SARS-CoV-2 RdRp (PDB ID: 6M71) with a binding energy of -8.0 kcal/mol and a K_i of 1.39 μM, indicating that it has potential inhibitory activity against this viral polymerase^[1].
Catechin-5-O-gallate binds to the ATP-binding site of SARS-CoV-2 helicase (PDB ID: 6ZSL) with a binding energy of -8.7 kcal/mol and a K_i of 0.43 μM, indicating its potential inhibitory activity against this viral enzyme^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.