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Cat. No.: HY-175907

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CBP/p300 ligand 7

CBP/p300 ligand 7 is a p300/CBP ligand that can be used for the synthesis of PROTACs, such as QC-182 (HY-162259).

For research use only. We do not sell to patients.

CAS No.: 2832963-93-4
Formula: C₂₈H₂₉F₂N₅O₂
Molecular Weight:505.56

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

CBP/p300 ligand 7 Chemical Structure

CAS No.: 2832963-93-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

CBP/p300 ligand 7 is a p300/CBP ligand that can be used for the synthesis of PROTACs, such as QC-182 (HY-162259)^[1].

IC₅₀ & Target^[1]

CBP/p300

All Histone Acetyltransferase Isoforms :

Chemical Information

CAS No. 2832963-93-4
Molecular Weight 505.56
Formula C₂₈H₂₉F₂N₅O₂
SMILES

CC1=NOC(C)=C1C2=CC=C(C(N=C3[C@H]4N(C5=CC(F)=C(F)C=C5)C(CCC4)=O)=C2)N3C6CCNCC6
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Chang Q, et al. Discovery of Novel PROTAC Degraders of p300/CBP as Potential Therapeutics for Hepatocellular Carcinoma. J Med Chem. 2024 Feb 22;67(4):2466-2486. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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CBP/p300 ligand 7

All Histone Acetyltransferase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

CBP/p300 ligand 7 Related Classifications

HY-175907 Related Classifications