CBP/p300 ligand-Linker Conjugate 3

Cat. No.: HY-186064: Ficha de datos Instrucciones de manejo
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CBP/p300 ligand-Linker Conjugate 3 is an Target Protein Ligand-Linker Conjugate that incorporates a ligand for CBP/p300 and a PROTAC linker, which recruits E3 ligases. CBP/p300 ligand-Linker Conjugate 3 can be used for synthesis of PROTAC CBP/P300 Degrader-2 (HY-181261).

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CBP/p300 ligand-Linker Conjugate 3 Estructura química

No. CAS : 3102127-04-5

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Descripciòn	CBP/p300 ligand-Linker Conjugate 3 is an Target Protein Ligand-Linker Conjugate that incorporates a ligand for CBP/p300 and a PROTAC linker, which recruits E3 ligases. CBP/p300 ligand-Linker Conjugate 3 can be used for synthesis of PROTAC CBP/P300 Degrader-2 (HY-181261)^[1].
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. CBP/p300 ligand-Linker Conjugate 3 Related Antibodies
Peso molecular	587.70
Fòrmula	C₃₄H₃₉F₂N₅O₂
No. CAS	3102127-04-5
SMILES	CC(C(N(C1=C2)C)=O)=CC1=C(N3CCCC(C=C4C5=CN(C6CCNCC6)N=C5)=C3C=C4C(F)F)C=C2C7CCOCC7
Envío	Room temperature in continental US; may vary elsewhere.
Almacenamiento	Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación	Ficha de datos (271 KB) Instrucciones de manejo (2659 KB)
Referencias	[1]. Chandrasekhar ABBINENI, et al. Substituted heterocyclic compounds and their derivatives as cbp and/or p300 degraders. WO2025202979A1.