CGP 54626 hydrochloride
Based on 2 publication(s) in Google Scholar
CGP 54626 (hydrochloride) is a selective antagonist of GABAB receptor with an IC50 value of 4 nM. CGP 54626 (hydrochloride) can be used to investigate the role of GABAB receptors in neurological signaling.
For research use only. We do not sell to patients.
- Purity: 99.76%
- CAS No.: 149184-21-4
- Formula: C18H29Cl3NO3P
- Molecular Weight:444.76
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Publications Citing Use of MedChemExpress (MCE) CGP 54626 hydrochloride
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | IC50 |
6.4 nM
Compound: CGP-54626
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Displacement of [3H]CGP54626 from human recombinant GABAB1A receptor expressed in CHO cells after 3 hrs
Displacement of [3H]CGP54626 from human recombinant GABAB1A receptor expressed in CHO cells after 3 hrs
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[PMID: 23403082] |
Chemical Information
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CAS No. 149184-21-4
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Appearance Solid
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Molecular Weight 444.76
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Formula C18H29Cl3NO3P
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Color White to off-white
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SMILES
O=P(C[C@@H](O)CN[C@H](C1=CC=C(Cl)C(Cl)=C1)C)(CC2CCCCC2)O.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Publications (2)
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Journal Impact Factor
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Most Recent
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J Clin Invest
Chromosomal 3q amplicon encodes essential regulators of secretory vesicles that drive secretory addiction in cancer. [Abstract]2024 Apr 25;134(12):e176355. PMID: 38662435 -
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)