Benzamide-15N
Based on 1 Customer Validation
Benzamide-15N is a 15N-labeled Benzamide. Benzamide inhibits poly(ADP-ribose) polymerase (PARP).
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- Reinheit: 99.87%
- CAS. Nr.: 31656-62-9
- Formel: C7H715NO
- Molecular Weight:122.13
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 31656-62-9
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Unlabeled Cas 55-21-0
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Appearance Solid
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Molecular Weight 122.13
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Formel C7H715NO
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Color White to off-white
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SMILES
O=C([15NH2])C1=CC=CC=C1
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Synonyms
Benzenecarboxamide-15N; Phenylamide-15N
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (818.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Cosi C, et al. Benzamide, an inhibitor of poly(ADP-ribose) polymerase, attenuates methamphetamine-induced dopamine neurotoxicity in the C57B1/6N mouse. Brain Res. 1996;735(2):343-348. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 8.1880 mL | 40.9400 mL | 81.8800 mL | 204.6999 mL |
| 5 mM | 1.6376 mL | 8.1880 mL | 16.3760 mL | 40.9400 mL | |
| 10 mM | 0.8188 mL | 4.0940 mL | 8.1880 mL | 20.4700 mL | |
| 15 mM | 0.5459 mL | 2.7293 mL | 5.4587 mL | 13.6467 mL | |
| 20 mM | 0.4094 mL | 2.0470 mL | 4.0940 mL | 10.2350 mL | |
| 25 mM | 0.3275 mL | 1.6376 mL | 3.2752 mL | 8.1880 mL | |
| 30 mM | 0.2729 mL | 1.3647 mL | 2.7293 mL | 6.8233 mL | |
| 40 mM | 0.2047 mL | 1.0235 mL | 2.0470 mL | 5.1175 mL | |
| 50 mM | 0.1638 mL | 0.8188 mL | 1.6376 mL | 4.0940 mL | |
| 60 mM | 0.1365 mL | 0.6823 mL | 1.3647 mL | 3.4117 mL | |
| 80 mM | 0.1023 mL | 0.5117 mL | 1.0235 mL | 2.5587 mL | |
| 100 mM | 0.0819 mL | 0.4094 mL | 0.8188 mL | 2.0470 mL |
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